# Main Menus
# Entry List
The Entry List is a list of all of the structures that have been loaded into the environment.
The Load, Plugin, Display, Color, Modify, Select, and Macro Menus can be displayed by clicking their respective icons located at the bottom of the Entry List.
# Quest Limiter
The Quest Limiter is an indicator that shows how close the current amount of atoms is to hitting the limit of Quest's computing capability. This indicator only shows up in the Quest version of Nanome software. When the amount of atoms approaches or hit the limit, the following prompts will show up.
# Hierarchy Menu
Hierarchy menus lists out the component of an entity, such as chains and residues, in hierarchical levels.
# Different Browsing Modes (Small, Medium, Large)
Different Viewing Modes can be toggled to modify the substructure icon sizes in each menu.
# Frame Data
Frame data allows users to navigate and modify different frames of the same structure (Academic and Enterprise only).
# Electron Density Maps
The Electron Density tab shows the configuration of viewing the Electron Density Map of the structure (Academic and Enterprise only).
# Menu Actions
|Select or deselect all present structures.|
|Invert current selection.|
|Lock or unlock selected entities.|
|Show or hide the box frame of selected entities.|
|Show or hide the selected entities.|
|Save the current workspace.|
|Discard the current workspace and create a new one.|
|Export the selected structures in a desired format.|
|Align the selected entities and place them in the same position under the same coordinate system. Caution: this does not necessarily align the entities by their atom position, and the entities could end up not overlapping after the alignment.|
|View the seqences of multiple chains and align them.|
|Delete the selected entities.|
Load molecules or structures into your workspace. Supported file formats include: .pdb, .cif, .mmcif, .sdf, .mol, .xyz, .mol2, .ccp4, .dsn6, .dcd, .gro, .pqr, .trr, .xtc, .psf, .pse, .nanome, .png, .jpg, .jpeg, .pdf
Workspaces that contain featured structures and tutorials.
Molecules featured by Nanome for their interesting properties or background.
From the Database tab, structures can be directly loaded from RCSB, DrugBank (Academic and Enterprise only), or Pubchem (Academic and Enterprise only). Custom database can also be added by changing the config file.
From the Keyword tab, structure can be loaded from a keyword search.
# My Files
My Files tab allows users to load structures from their local directory.
Recent files loaded in Nanome.
This tab contains options for the visual of atoms and bonds.
|Hide atoms and show bonds in thin wire visual.|
|Show small atoms and bonds in volumetric stick visual.|
Van Der Waals
|Show atoms in thin Van Der Waals visual and hide bonds.|
|Show atoms with radius proportion to their color value and hide bonds.|
Ball & Stick
|Hide all atoms and bonds.|
This tab contains options for the visual of ribbons.
|Show ribbon in cartoon visual that highlight secondary structures using helix and arrows.|
|Show ribbon in uniform tube visual.|
|Show ribbon in tube with widths proportion to the atoms' color value.|
Toggle the visibility of solvent-excluded-surface or change its opacity.
# Sub Structure
|Show hetatoms, including water.|
|Show labels on atoms.|
|Show labels on residues.|
Apply a solid color or a color scheme on the selected structures.
Colors picked in picker are applied in a solid style.
|Carbonite color applies only to carbons.|
|Monochrome color applies to all atoms indifferently.|
Colors picked in schemes are applied in a certain pattern.
- YRB Hydrophobe
Color selected structures by their hydrophobicity with yellow, red, blue colors.
Color selected antibody structures by their regions.
Other available color schemes include coloring by occupancy, b-factor, rainbow and so on.
Edit the selected structures by applying actions from the buttons.
Apply certain computations on the selected structures and modify them according to the result.
- Calculate ESP
Generate the Electron Potential Map of the selected structure.
- Calculate Clashes
Config the tolerance of atom clashes.
- Calculate Hbond
Config the threshold for generating h-bonds.
Config forcefield and step for minimizing potential energy of selected structures.
Switch to a certain tool to directly apply modification to the structures.
Mutate the R-groups of the selected amino acids.
Quickly modify selection range using certain criteria.
Refine selection by applying certain changes.
- Replace Selection
# Atom Type
Select or deselect certain types of atoms.
# Residue Type
Select or deselect certain types of residues.
Expand or shrink the selection range by physical proximity.